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antiparasitic agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (6) Apoptosis (4) Bacterial (7) Fungal (1) GABA Receptor (2) Glutathione S-transferase (1) HIF/HIF Prolyl-Hydroxylase (2) Isotope-Labeled Compounds (4) Microtubule/Tubulin (2) Mitochondrial Metabolism (1) Necroptosis (2) Oxidative Phosphorylation (2) p38 MAPK (2) Parasite (52) Phosphatase (3) Raf (2) Reverse Transcriptase (2) SARS-CoV (3) Sirtuin (2) Topoisomerase (2)
By Research Areas:	Cancer (6) Cardiovascular Disease (2) Infection (52) Inflammation/Immunology (1) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-149960

Antiparasitic agent-17	Parasite	Infection
Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC₅₀s of 0.96 μM and 1.67 μM, respectively .

HY-149078

Antiparasitic agent-14	Parasite	Infection
Antiparasitic agent-14 is a potemt *antiparasitic* agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote .

HY-151133

Antiparasitic agent-9	Parasite	Infection
Antiparasitic agent-9 (compound 47) is an orally active and potent antiparasitic agent. Antiparasitic agent-9 shows antiparasitic activity against the human parasite .

HY-151433

Antiparasitic agent-10	Parasite	Infection
Antiparasitic agent-10 (Compound 94) is an *anti-parasitic* agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research .

HY-157028

Antiparasitic agent-19	Others	Infection
Antiparasitic agent-19 (compound 40) is a compound with broad-spectrum antiparasitic activity. Antiparasitic agent-19 has minimal toxicity against Trypanosoma brucei, Leishmania Infantum, and Trypanosoma cruzi .

HY-147806

Antiparasitic agent-8

Parasite Infection

Antiparasitic agent-8 (Compound 9) is an antiparasitic agent against Hymenolepis nana with low cytotoxicity .

Antiparasitic agent-8	Parasite	Infection
Antiparasitic agent-8 (Compound 9) is an antiparasitic agent against Hymenolepis nana with low cytotoxicity .

HY-157466

Antiparasitic agent-21	Parasite	Infection
Antiparasitic agent-21 (compound 28) has selectively antiparasitic activity against Naegleria fowleri with an EC₅₀ of 0.92 μM. Antiparasitic agent-21 has excellent blood-brain barrier permeability .

HY-149722

Antiparasitic agent-20	Parasite	Infection
Antiparasitic agent-20 (Compound 1p) is a parasite inhibitor with broad antiparasitic activity. Antiparasitic agent-20 has inhibitory effects on T. brucei and T. cruzi with EC₅₀ values of 0.09 μM and 14.1 μM respectively .

HY-126295

Anti-parasitic agent 3

Parasite Infection

Anti-parasitic agent 3 is an anti-parasitic agent which active against agent resistant parasites.

Anti-parasitic agent 3	Parasite	Infection
Anti-parasitic agent 3 is an anti-parasitic agent which active against agent resistant parasites.

HY-146044

Antiparasitic agent-6	Parasite	Infection
Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC₅₀ = 13.64 μM) .

HY-146043

Antiparasitic agent-5	Parasite	Infection
Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC₅₀ = 6.78 μM) .

HY-146045

Antiparasitic agent-7	Parasite	Infection
Antiparasitic agent-7 (compound 5d) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 2.85 μM. Antiparasitic agent-7 also has certain cytotoxicity against HepG2 (CC₅₀ = 10.61 μM) .

HY-149079

Antiparasitic agent-15	Parasite Necroptosis	Infection
Antiparasitic agent-15, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-15 has IC₅₀s of 0.9 μM and 0.64 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-15 has IC₅₀s of 42.2 μM and 9.58 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-15 induces parasite cell death through necrosis induction. Antiparasitic agent-15 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes .

HY-149080

Antiparasitic agent-16	Parasite Necroptosis	Infection
Antiparasitic agent-16, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-16 has IC₅₀s of 1.0 μM and 0.6 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-16 has IC₅₀s of 150.2 μM and 16.75 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-16 induces parasite cell death through necrosis induction. Antiparasitic agent-16 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes .

HY-146042

Antiparasitic agent-4	Parasite	Infection
Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC₅₀s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC₅₀ = 18.97 μM) .

HY-146041

Antiparasitic agent-2	Parasite	Infection
Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC₅₀s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC₅₀ = 26.79 μM) .

HY-155281

Antiparasitic agent-18	Parasite	Infection
Antiparasitic agent-18 (compound 3a) is active and selective against the T. brucei (EC₅₀=0.4 μM), T. cruzi (EC₅₀=0.21 μM), and L. donovani (EC₅₀=0.26 μM). Antiparasitic agent-18 has potent antiprotozoal activity .

HY-B0413

Fenbendazole 5 Publications Verification	Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic	Infection
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad *antiparasitic* range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

HY-B0413S

Fenbendazole-d3 2 Publications Verification	HIF/HIF Prolyl-Hydroxylase Parasite Microtubule/Tubulin Antibiotic	Infection
Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].

HY-101590

Symetine

L 16726
Parasite Infection

Symetine is an antiparasitic and antispirochete agent.
HY-B0945

Nitromide

1 Publications Verification

3,5-Dinitrobenzamide
Parasite Infection

Nitromide is an anti-parasitic agent.
HY-139587

Umifoxolaner

ML-878
Parasite Infection

Umifoxolaner is an anti-parasitic agent (veterinary).
HY-18716

Dextrorotation nimorazole phosphate ester

Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent.

Symetine L 16726	Parasite	Infection
Symetine is an *antiparasitic* and antispirochete agent.

Nitromide 1 Publications Verification 3,5-Dinitrobenzamide	Parasite	Infection
Nitromide is an anti-parasitic agent.

Umifoxolaner ML-878	Parasite	Infection
Umifoxolaner is an anti-parasitic agent (veterinary).

Dextrorotation nimorazole phosphate ester
Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent.

HY-B1194

Tetramisole hydrochloride (±)-Tetramisole hydrochloride; DL-Tetramisole hydrochloride; R-829	Parasite Phosphatase Antibiotic	Infection
Tetramisole hydrochloride inhibits alkaline phosphatase and is a highly pure antiparasitic agent.

HY-109077

Tigolaner

BAY-1272858
GABA Receptor Parasite Infection Neurological Disease

Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent .

Tigolaner BAY-1272858	GABA Receptor Parasite	Infection Neurological Disease
Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent .

HY-B0263S

Thiabendazole-d4 2-(4-Thiazolyl)benzimidazole-d₄	Mitochondrial Metabolism Parasite	Others
Thiabendazole-d₄ is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].

HY-N7227

Anonaine

Glutathione S-transferase Parasite Infection Cancer

Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .
HY-155087

Anticancer agent 140

Parasite Infection Cancer

Anticancer agent 140 (Compd 3) is a compound with potential anticancer and antiparasitic activities .
HY-17598S

Rafoxanide-13C6

Isotope-Labeled Compounds Parasite Infection

Rafoxanide ¹³C₆ is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent[1].

Anonaine	Glutathione S-transferase Parasite	Infection Cancer
Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .

Anticancer agent 140	Parasite	Infection Cancer
Anticancer agent 140 (Compd 3) is a compound with potential anticancer and antiparasitic activities .

Rafoxanide-13C6	Isotope-Labeled Compounds Parasite	Infection
Rafoxanide ¹³C₆ is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent[1].

HY-109077S

Tigolaner-d4	Isotope-Labeled Compounds GABA Receptor Parasite	Infection Neurological Disease
Tigolaner-d₄ is deuterium labeled Tigolaner. Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent[1].

HY-15308

Avermectin B1a

Abamectin B1a
Parasite Antibiotic Infection

Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.

Avermectin B1a Abamectin B1a	Parasite Antibiotic	Infection
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.

HY-122975

Metronidazole Benzoate Benzoyl metronidazole	Bacterial Parasite	Infection
Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent .

HY-118495

Cardol diene

Parasite Infection

Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .

Cardol diene	Parasite	Infection
Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .

HY-146747

Antifungal agent 26	Fungal Parasite	Infection Inflammation/Immunology
Antifungal agent 26, a Pradimicin A derivative, shows antifungal, antiviral, and antiparasitic activities through binding to d-mannose (Man)-containing glycans of pathogenic species .

HY-125729

Ivermectin B1b	Parasite SARS-CoV	Infection
Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture .

HY-129130

Canthin-6-one N-oxide

Canthin-6-one 3-oxide
Parasite Infection

Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active antiparasitic agent with limited activity .

Canthin-6-one N-oxide Canthin-6-one 3-oxide	Parasite	Infection
Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active *antiparasitic* agent with limited activity .

HY-122382

Levofuraltadone NF-602	Parasite Bacterial	Infection
Levofuraltadone (NF-602) is an antibacterial and antiparasitic agent. Levofuraltadone has anti-trypanosomiasis activity and can be used in the study of human african trypanosomiasis as well as bacterial infections .

HY-14932

Pafuramidine 1 Publications Verification DB289	Parasite Antibiotic	Infection
Pafuramidine (DB289) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria .

HY-122975R

Metronidazole Benzoate (Standard) Benzoyl metronidazole (Standard)	Bacterial Parasite	Infection
Metronidazole Benzoate (Standard) is the analytical standard of Metronidazole Benzoate. This product is intended for research and analytical applications. Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent .

HY-14932A

Pafuramidine maleate DB289 maleate	Parasite Antibiotic	Infection
Pafuramidine (maleate) (DB289 (maleate)) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine (maleate) (DB289 (maleate)) is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria .

HY-146487

Anti-infective agent 1	Bacterial Parasite	Infection
Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .

HY-146489

Anti-infective agent 3	Bacterial Parasite	Infection
Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL .

HY-17532

Haloxon	Parasite	Infection
Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium .

HY-146488

Anti-infective agent 2	Parasite Bacterial	Infection
Anti-infective agent 2 (compound 3k) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 0.07 and 2.20 μM, respectively. Anti-infective agent 2 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 32 μg/mL .

HY-N10441

3β-Hydroxy-hop-22(29)-ene	Parasite	Infection
3β-Hydroxy-hop-22(29)-ene (compound 3) is a potent *antiparasitic* agent. 3β-Hydroxy-hop-22(29)-ene shows moderate activity against Trypanosoma cruzi and Leishmania mexicana .

HY-128554S

N-Desethyl amodiaquine-d5	Isotope-Labeled Compounds Parasite	Infection
N-Desethyl amodiaquine-d₅ is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

HY-128554S1

N-Desethyl amodiaquine-d5 dihydrochloride	Isotope-Labeled Compounds Parasite	Infection
N-Desethyl amodiaquine-d₅ (dihydrochloride) is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

HY-128554

N-Desethyl amodiaquine	Parasite	Infection
N-Desethyl amodiaquine is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine is an *antiparasitic* agent, has inhibitory for strains V1/S and 3D7 with IC₅₀ values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine can be used for the research of malaria .

HY-128554A

N-Desethyl amodiaquine dihydrochloride	Parasite	Infection
N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine dihydrochloride is an *antiparasitic* agent, has inhibitory for strains V1/S and 3D7 with IC₅₀ values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine dihydrochloride can be used for the research of malaria .

HY-B0226A

(E)-Nitrofurazone (E)-Nitrofural	Bacterial Parasite	Infection
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7227

Anonaine	Structural Classification Alkaloids Annona crassiflora Mart. Source classification Quinoline Alkaloids Plants Annonaceae	Glutathione S-transferase Parasite
Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .

HY-118495

Cardol diene	Structural Classification Source classification Phenols Polyphenols Plants Anacardium occidentaleL. Anacardiaceae	Parasite
Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .

HY-129130

Canthin-6-one N-oxide Canthin-6-one 3-oxide	Structural Classification Alkaloids Simaroubaceae Other Alkaloids Source classification Eurycoma harmandiana Pierre Plants	Parasite
Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active *antiparasitic* agent with limited activity .

HY-N10441

3β-Hydroxy-hop-22(29)-ene	Cnidoscolus spinosus Lundell Triterpenes Terpenoids Source classification Euphorbiaceae Plants	Parasite
3β-Hydroxy-hop-22(29)-ene (compound 3) is a potent *antiparasitic* agent. 3β-Hydroxy-hop-22(29)-ene shows moderate activity against Trypanosoma cruzi and Leishmania mexicana .

Cat. No.	Product Name	Chemical Structure

HY-B0413S

Fenbendazole-d3

2 Publications Verification

Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].

HY-B0263S

Thiabendazole-d4

Thiabendazole-d₄ is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].

HY-128554S

N-Desethyl amodiaquine-d5
N-Desethyl amodiaquine-d₅ is the deuterium labeled N-Desethyl amodiaquine. N-Desethyl amodiaquine is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

HY-17598S

Rafoxanide-13C6

Rafoxanide ¹³C₆ is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent[1].
HY-109077S

Tigolaner-d4

Tigolaner-d₄ is deuterium labeled Tigolaner. Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent[1].

HY-128554S1

N-Desethyl amodiaquine-d5 dihydrochloride
N-Desethyl amodiaquine-d₅ (dihydrochloride) is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

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